Organic phosphoric acids and derivatives
Medchemexpress LLC Povorcitinib phosphate | 1637677-33-8 | 98.8% | C23H25F5N7O5P | 1 ML
Povorcitinib phosphate is a potent and selective JAK1 inhibitor. It is effective in reducing abscesses and inflammatory nodules and can be utilized for studying cutaneous lupus erythematosus (CLE) and lichen planus (LP). It regulates the expression of TNF-α and TGF-β, thereby exhibiting anti-inflammatory activity. In vivo studies have shown that it alleviates liver inflammation and pathological damage and prolongs survival rate in Down Syndrome (DS) carrying Dp16 mouse models.
- Potent and selective JAK1 inhibitor
- Effective in reducing abscesses and inflammatory nodules
- Regulates the expression of TNF-α and TGF-β
- Exhibits anti-inflammatory activity
- Alleviates liver inflammation and pathological damage
- Prolongs mouse survival rate in Dp16 mouse models
Medchemexpress LLC 4-Nitrophenyl phosph 100mg | 330-13-2 | 219.09 g·mol⁻¹ | C6H6NO6P | 100 MG
4-nitrophenyl phosphate is a chromogenic phosphatase substrate (CAS 330-13-2) that, upon enzymatic hydrolysis, yields the yellow 4-nitrophenolate ion measured at 405 nm. It is used for monitoring phosphatase activity, enzyme kinetics, and inhibitor screening.
- Generates a measurable yellow product (4-nitrophenolate) detectable at 405 nm.
- Applicable to generic phosphatase and protein tyrosine phosphatase assays.
- High purity for biochemical assays (COA reports ~99.5% by LC-MS).
- Available in small pack sizes to support assay optimization.
- Solid, stable substrate appropriate for spectrophotometric readouts.
Apexbio Technology LLC Rilmenidine Phosphate 85409-38-7 25mg
Rilmenidine phosphate (CAS 85409-38-7) is a water-soluble derivative of rilmenidine that selectively targets imidazoline I1 receptors non-adrenergic high-affinity binding sites implicated in blood pressure regulation Activation of I1 receptors modulates sympathetic outflow resulting in antihypertensive effects observed in both preclinical models and clinical studies In Hep G2 cells rilmenidine attenuates stearic acid-induced lipid accumulation associated with p38 MAPK activation and increased FXR expression In high-fat diet-fed mice rilmenidine ameliorates hepatic steatosis through imidazoline I1 receptor-mediated pathways This compound is of interest for investigating cardiovascular and metabolic disease mechanisms
eMolecules 950596-58-4 | 2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile | MFCD16619377 | 1g
Ambeed | 2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile | 1g | 552586227 | A148074 | 950596-58-4 | MFCD16619377 | 266.297 | C13H18N2O4
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Medchemexpress LLC Dibutyl phenyl phosphate | 2528-36-1 | MFCD00438060 | 99.0% | 286.30 g·mol⁻¹ | C14H23O4P | 5 MG
Dibutyl phenyl phosphate is an organophosphate research reagent used primarily as a flame retardant and studied for biological activity. It is reported to inhibit butyrylcholinesterase (BChE) with IC50 83.6 μM and Ki 94.5 μM. Intended for research use only and not for human or clinical applications.
- Organophosphate flame retardant.
- Reported BChE inhibitor (IC50 83.6 μM; Ki 94.5 μM).
- Chemical formula C14H23O4P; molecular weight 286.30 g·mol⁻¹.
- CAS number 2528-36-1 for unambiguous identification.
- Supplied in milligram-scale quantities suitable for laboratory assays.
- Intended for research use only; follow safety data sheet guidance for handling.
Apexbio Technology LLC KN-92 phosphate 1135280-28-2 50mg
KN-92 phosphate is a small-molecule analog of the Ca2 /calmodulin-dependent kinase II (CaMKII) inhibitor KN-93 It is designed as an inactive control compound to distinguish CaMKII-specific effects in experimental settings KN-92 phosphate does not inhibit CaMKII activity and thus serves as a negative control for CaMKII inhibition studies Additionally KN-92 phosphate blocks certain voltage-gated potassium (Kv) channels such as Kv1 2 and Kv1 5 reducing steady-state current amplitudes upon depolarization Based on these pharmacological properties KN-92 phosphate holds research potential in investigating mechanisms underlying CaMKII-related signaling pathways and Kv channel functions
Medchemexpress LLC Dibenzyl hydrazodicarboxylate | 5394-50-3 | MFCD00022028 | 300.31 | C16H16N2O4 | 10 MG
Dibenzyl hydrazodicarboxylate is a small-molecule protein cross-linking reagent supplied for research use. It is used to cross-link proteins and other biomolecules in biochemical and structural studies.
- Protein cross-linking reagent for biochemical applications.
- CAS number 5394-50-3; molecular formula C16H16N2O4; molecular weight 300.31.
- Storage: powder at -20°C (3 years) or 4°C (2 years); in solvent at -80°C (6 months) or -20°C (1 month).
- For research use only; not for human or clinical use.
- Purity and appearance not specified by the manufacturer.
Medchemexpress LLC Dimethyl phosphate-13C2 (sodium) | 157487-95-1 | MFCD29036736 | 98.2% | 150.02 g·mol-1 | 13C2H6NaO4P | 500ug
Dimethyl Phosphate-13C2 (sodium) is 13C labeled Dimethyl Phosphate (sodium)[1]
Medchemexpress LLC Pyridoxal | 66-72-8 | MFCD00464806 | 100.0% | 167.16 | C8H9NO3 | 25 MG
Pyridoxal is an analytical standard of pyridoxal (a form of vitamin B6) provided as a high-purity reference material for research and analytical applications. It is intended for method development, calibration, and quantitative or qualitative assays.
- High purity (99.97%) suitable for analytical use.
- Supplied in small, well-defined packs; 25 MG available.
- Compatible with HPLC, GC, and MS methods.
- Molecular weight 167.16 and chemical formula C8H9NO3.
- Useful for studies of vitamin B6 metabolism and related biochemical assays.
Medchemexpress LLC Pyridoxal 5'-phosphate monohydrate | MFCD00149414 | 99.8% | 25 G
Pyridoxal 5'-phosphate monohydrate is provided as an off-white to light yellow solid. This product is intended for research use only and has not been fully validated for medical applications. It should be stored in a cool, well-ventilated area, sealed away from moisture, and protected from direct sunlight.
- Appearance: Off-white to light yellow solid
- Purity (HPLC): 99.8%
- Recommended storage: 4°C, sealed, away from moisture
- In solvent storage: -80°C for 6 months; -20°C for 1 month
- Harmful if swallowed
- Causes skin irritation
- Causes serious eye irritation
- May cause respiratory irritation